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Medicine and juice a bad mix?
Filed under: Health & Safety: Babies, Medical Conditions, In The News
Having a sick child is no fun for anyone and we all try to avoid it as best we can. For me, not wanting my 7-year-old to get sick is more than about not wanting her to feel bad and maybe miss a day or two of school. It's the medicine. Getting meds down her throat is almost as difficult as bathing the cat. But with the cat, I can at least employ some brute force to get it done. With Ellie, I have a more subtle bag of tricks involving child psychology, bribes and usually something sweet to help wash it down. That something sweet is often juice, which according to new research, might not actually be the best way to help the medicine go down.
Grapefruit juice has long been known to interact with some drugs in a way that can cause blood concentration of the medication to reach toxic levels. But a new study has found that grapefruit and other fruit juices may also block the effects of some drugs. In the study, which was conducted with adult patients, grapefruit, orange and apple juices were found to reduce the absorption of the anticancer drug etoposide; certain beta blockers; cyclosporine, which is used to prevent rejection of transplanted organs; and some antibiotics.
"This is just the tip of the iceberg," says Dr. David G. Bailey, a professor of clinical pharmacology at the University of Ontario. "I'm sure we'll find more and more drugs that are affected this way."
Dr. Bailey recommends taking most medications with water and advises patients to consult their doctor or pharmacist before taking any medications with grapefruit or other juices.
Grapefruit juice has long been known to interact with some drugs in a way that can cause blood concentration of the medication to reach toxic levels. But a new study has found that grapefruit and other fruit juices may also block the effects of some drugs. In the study, which was conducted with adult patients, grapefruit, orange and apple juices were found to reduce the absorption of the anticancer drug etoposide; certain beta blockers; cyclosporine, which is used to prevent rejection of transplanted organs; and some antibiotics.
"This is just the tip of the iceberg," says Dr. David G. Bailey, a professor of clinical pharmacology at the University of Ontario. "I'm sure we'll find more and more drugs that are affected this way."
Dr. Bailey recommends taking most medications with water and advises patients to consult their doctor or pharmacist before taking any medications with grapefruit or other juices.
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ReaderComments (Page 1 of 1)
8-21-2008 @ 1:11PM
LS said...Your dilemma makes me think of two things that might help... first, talk with your pharmacist, sometimes they can make drugs for children in a more palatable form, such as flavored syrups or chewable tablets.
Second, talk with your doctor/pharmacist and see if something like a flavored water will do the trick. Some are very tasty, and have just enough flavor to sweeten, but perhaps not enough juice (some, none at all), to affect the meds.
Or you could just wrap the pill in cheese, or stick it in a wad of peanut butter - that always works for my dog.....
:)
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8-21-2008 @ 8:19PM
Derek said...My son is in the process of getting a liver transplant, and one of the things the doctor told us is that he will never be able to have grapefruit juice because of the adverse reactions it has against his anti-rejection medication.
FYI SunnyD and many other juices use grapefruit as an additive.
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